Sentence examples for class of entry from inspiring English sources
These findings provide guidance for the design and structural modifications of these derivatives for better anti-HIV-1 activity which is important for the development of a new class of entry inhibitors.
This process occurs roughly in three phases, each of which can be inhibited by a class of entry inhibitors.
The intramolecularly assembled conjugate holds promise for determining the high-resolution crystal structure of the peptide triazole class of entry inhibitors in complex with gp120.
CCR5 antagonists are the newest agents that have entered the HIV armamentarium and the second class of entry inhibitors to gain regulatory approval.
Descriptive data showed diverse immigrant profiles across the nine source regions for a number of characteristics that can affect service use, such as English language proficiency and visa admission class of entry.
However, socially mobile individuals were twice as likely to report levels of wellbeing that resembled non-mobile individuals in their social class of entry (or current class), rather than their prior class.
Different classes of entry inhibitors have been developed as alternatives for those failing therapy.
Among the three classes of entry inhibitors discussed here, antibodies are the most advanced in terms of development.
Given a feature in a binary-class dataset x = x 1 ⋯ x n 1 + 1 ⋯ y n 1 + n 2 in X *, the t-statistic is calculated as t = | x ¯ - y ¯ | / s x 2 / n 1 + s y 2 / n 2, where x ¯, y ¯, s x 2, s y 2 are the mean and variance values of the two classes of entries in the feature x.
The knowledge of this mechanism of HIV entry into cells has resulted in the development of a new class of ARVs entry inhibitors, aimed at blocking the CCR5, CCR2, or CXCR4 coreceptors.
This observation gave impetus to the development of small molecular weight antagonists and led to the approval of maraviroc, the first of a new class of virus entry inhibitors, for use in drug-resistant CCR5-tropic HIV-1 infection in 2007.
