In addition, there is a sub-class of ADHESION MOLECULES called INTEGRINS.
The two primary classes of adhesion molecules involved in the adhesion cascade are selectins (responsible for rolling) and integrins/immunoglobulins (responsible for adhesion).
Among the classes of adhesion molecules, desmosomes have been widely recognized and studied for their various roles in cell adhesion, tissue morphogenesis, and cell signaling [ 3].
Despite its 'presumed presence' the inability to detect or visualise dystroglycan in other classes of adhesion has hampered further investigation in this area.
Here we show that, immediately following wounding, basal keratinocytes upregulate ephrin-Bs and EphBs, which leads to the dissolution of several classes of adhesion junctions between neighboring epidermal cells, and this loosening enables polarized migration.
The apCAM's are members of the immunoglobulin class of cell adhesion molecules and resemble two neural cell adhesion molecules, NCAM and fasciclin II.
We describe the structure and function of the toposome, a modified calcium-binding, iron-less transferrin, the first member of a new class of cell adhesion proteins.
Our results suggest that the cadherin class of cell adhesion molecules in general, and E-cadherin in particular, may play a key role in the biology of malignant gliomas.
It has been proposed that presynaptic differentiation induced by APP involves intracellular association with Cask and Mint1 [31], similarly to neurorexin/neuroligin (NX/NL) and SynCAM class of synaptic adhesion proteins [53], [54], [55].
Finally, the integrin class of cell adhesion molecules has been implicated in ethanol-induced behaviors.
Moreover, the initial attachment of metastatic cells to bone endothelial cells is largely attributed to the lectin class of protein adhesion molecules.
