Overlap between CLASH Targets and Experimentally Validated miRNA Targets from Published Databases To check if our CLASH data set contains known, experimentally validated miRNA targets we compared it with two databases – miRTarBase (Hsu et al., 2011 ) and TarBase (Vergoulis et al., 2012 ).
Clash data accrued (in mm) was subsequently quantitatively modelled using the probability density function (PDF) and the cumulative distribution function (CDF).
Although primarily designed for use with AGO CLASH data, hyb can also be used for the detection and annotation of chimeric reads in other high-throughput sequencing datasets.
The CLASH data set included a number of previously known interactions (Table S3).
Analysis of AGO1 crosslinking, ligation, and sequencing of hybrids (CLASH) data suggests tRF-5s and tRF-3s may interact with thousands of different RNAs in human cells.
We present the "hyb" bioinformatics pipeline, which we developed to analyse high-throughput cDNA sequencing data from CLASH experiments.
This study uses data from CLASH database and experimental campaigns, specifically carried out at Flanders Hydraulics Research (Belgium), in order to validate this approach.
In this study, the selected data from the CLASH database were used to provide new formulas for the estimation of wave overtopping at simple sloped inclined seawalls or dikes with smooth impermeable surface.
After August's long lull, the eurocrisis roared back into life today with the European Central Bank's new bond-buying programme, a warning from the OECD, depressing jobless data from France and Greece, and policemen clashing with other policemen in Athens.
An earlier legal challenge by Schrems — which was also related to the clash between US mass surveillance programs (which harvest data from social media services) and EU fundamental rights (which mandate that web users' privacy is protected) — resulted in the previous arrangement for transatlantic data flows being struck down by the CJEU in 2015, after standing for around 15 years.
