To clarify functions of the Mre11/Rad50 (MR) complex in DNA double-strand break repair, we report Pyrococcus furiosus Mre11 crystal structures, revealing a protein phosphatase-like, dimanganese binding domain capped by a unique domain controlling active site access.
In this paper, with the support of simulation results from the HFPN model, we clarify functions of HPr and EIIA Glc as key regulators of glucose and glycogen utilization.
CONCLUSIONS: Comparing the B. vafer genome with B. pennsylvanicus and B. floridanus refines the core genes shared within the mutualist group, thereby clarifying functions required across ant host species.
Comparing the B. vafer genome with B. pennsylvanicus and B. floridanus refines the core genes shared within the mutualist group, thereby clarifying functions required across ant host species.
Further investigation is needed to clarify the function and role of Spns2 in normal physiological conditions and in the pathological condition of cancer.
Further studies are aimed to clarify the function of this novel protein, and its role in the progression and metastasis of various cancers.
To clarify which function is primarily responsible for its essentiality and the protein domain for such function, we performed dRecQ4 functional domain dissection experiments.
Likewise, analysis of developmental disorders may clarify the function of different tubulin isotypes.
Selective inhibitors could help clarify the function of each isoform, and provide therapeutic agents having potentially fewer adverse effects.
They help clarify the function of FOXP2, and, in doing so, they help scientists better understand what constellation of genes produces the capacity for language in humans and, thus, how we differ from our nearest primate relative, the chimpanzee.
These results can clarify the function of core shell structure in core shell structured layered materials by excluding the effects of composition variation.
