In this respect, we believe, as far as 'need for RRT' is used as a relevant study endpoint, a standardised study protocol clarifying mode, dose, type of anticoagulation and rules for starting and stopping of RRT are mandatory.
Because of the rapidly expanding number of reservoir host adapted Bartonella spp. that have been discovered in recent years, efforts to clarify modes of transmission are relevant to public health in terms of interrupting the transmission process.
Using analysis of Bayesian estimation, we clarified the mode of generating clusters; e.g., cluster 2 was distinguished by the difference in features between the BS optimal solutions and the original optimal solution, whereas cluster 3 was distinguished by the substantial change in the shape of the response surfaces.
To clarify its mode of action, we studied in parallel the effects of a specific MMP inhibitor, marimastat.
Adams began by clarifying the mode of action of aspirin, which had been in use for pain and fever since 1900 but with no clear idea of how it worked.
To clarify the mode of action, their affinity for the quinazolinone/2,3-benzodiazepine site of the AMPA receptor complex has been assayed.
Therefore, this study was designed to clarify the mode of cell death following ischaemic osteonecrosis of the femoral head in an established pig model.
Further studies will also be required to clarify the mode of action of this therapeutic intervention.
Randomized sham controlled studies and larger and multicentre trials are needed in order to determine the optimal dosage and to clarify the mode of action.
Thus, these polyamides are likely to be promising broad spectrum antibacterial agents and deserve further investigation in order to clarify the mode of action at the molecular level.
