Your English writing platform
Discover LudwigSuggestions(1)
Exact(2)
Thank you for sending your work entitled "MutS/MutL crystal structure reveals that the mutS sliding clamp loads MutL onto DNA" for consideration at eLife.
[Editors' note: further revisions were requested prior to acceptance, as described below.] Thank you for resubmitting your work entitled "MutS/MutL crystal structure reveals that the mutS sliding clamp loads MutL onto DNA" for further consideration at eLife.
Similar(58)
Additionally, unique subunit-specific interactions between components of the clamp loader, RFC, suggest a model for clamp loading of PCNA.
Cdc6p is a member of the AAA+ superfamily of proteins, which includes the prokaryotic and eukaryotic clamp loading proteins.
This approach is demonstrated by considering how DNA polymerase clamp-loader AAA+ ATPases couple DNA recognition to ATP hydrolysis and clamp loading.
Recent determinations of the crystal structure of the Escherichia coli γ complex and δ β assembly have shed light on the bacterial clamp loading reaction.
The two clones with single C/L translocations analyzed here were obtained from sgs1Δ mutants with defects in the DNA damage checkpoint clamp (mec3Δ) or clamp loading (rad24Δ), which had previously been shown to yield C/L translocations [19].
DNA replication proteins include DNA polymerase delta, FEN-1, and the clamp loading complex replication factor C (RFC) that functions to assemble the three subunits of PCNA around the DNA duplex [9].
The problem would be acute if there were any lag between clamp loading and polymerase arrival.
However, such studies were often indirect and qualitative, failing to monitor clamp loading-unloading in real time.
However, there is some controversy regarding the stoichiometry of ATP usage in the T4 clamp loading cycle [ 94, 98, 103- 105].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com