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The results of some of the cited tools are summarized in a recent database called DriverDB [ 15] and also aggregated in one of the Pan- Canalysisalysis publications [ 16].
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The second most cited tool was the Downs and Black tool, with 962 citations since its introduction in 1998.
A number of studies have examined quality of life (QOL) through the perspective of other assessments of well-being, the most frequently cited tool being the SF-36.
The cited tools can be used for many other types of analyses than the ones looked at in this paper, which leads to a much more complex user interface and often overwhelms the user with many options.
Although SIFT and Polyphen are highly cited tools, comparative analyses carried out by Thusberg et al. and Shihab et al. found FATHMM, MutPred, and SNPs&GO to perform better using the VariBench benchmarking dataset containing missense mutations [ 43, 46].
Among the most frequently cited tools, a larger proportion (5/7) were PT tools compared with only two of the 19 general health research tools (i.e. Jadad and Chalmers).
It cited tools and treatments used by the DOD which had "no clear scientific evidence base" and said more needed to be done to evaluate their effectiveness.
Even if other sources and tools are cited, a more extensive explanation of these components of Veridical would help the reader/user.
For example, the initial draft did not address whether agencies should account for the effects of federal land and resource management decisions on carbon sequestration, whereas the 2014 draft and the final version direct agencies to consider such effects and cite tools that can be used to perform this analysis.
Constraints such as time, lack of knowledge and inadequate inherent safety analysis tools are often cited as obstacles to development and implementation of inherently safer design.
The oPOSSUM software is a highly cited tool for TFBS motif over-representation analysis (as assessed by Google Scholar citation counts), perhaps due to the ease of use and power of the approach.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com