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Considering X as the reference neuron (the one which actually makes Y to spike), then for each spike of X, a subsequent spike of Y is considered and cross-inter-spike-intervals were defined as time difference (cISI = tY−tX, cf., Figure 2B).
As only one polymerase molecule may be packaged per nucleocapsid, TP RT domain interactions normally occurs in cis, i.e., intramolecularly.
Once activated, transposition is relatively random, requiring only a target TA dinucleotide integration site and exhibiting some bias toward "jumping" in cis, i.e., within the same chromosome (Keng et al. 2005; Carlson et al. 2003; Horie et al. 2003).
Interestingly, the N-ethyl N-nitrosurea (ENU -induced rat modENU -inducedf1-/+;Tp53-/+ cis (i.e. B6-NPcis) mouse model have both shown males to develop MPNSTs at an earater age than femodel, even while andountheg for coNf1-/+ Tp53-/+ors such as pareNf1-/+ Tp53-/+ the B6-NPcis model [ 21, 24, 25].
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Methods for identifying statistically significant CISs, i.e. regions that are mutated by insertions in significantly more tumours than expected by chance, have involved generating a random distribution of insertions across the genome and obtaining an estimate of the number of false CISs in windows of fixed size using Monte Carlo simulation [214] or the Poisson distribution [175].
To identify common insertion sites (CISs), i.e., regions in the genome that are significantly more frequently mutated by insertions than would be expected by chance, we used a statistical framework based on Gaussian kernel convolution (GKC), which estimates a smoothed density distribution of inserts over the entire genome (de Ridder et al., 2006).
Commonly, eQTLs are differentiated in cis- (i.e. local) and trans- (i.e. distant) eQTLs.
All of the other cis women I know who have been called out of their gender identity (wearing a hoodie I have been called "sir" in supermarket parking lots) have also been tall and black.
(Ms. Streisand said in an e-mail message that she had not known it was a gay club and "just thought it odd that my friend Cis and I were the only women there").
The degradation of polymer main chain in solution was always accompanied by the decrease of cis content, i.e. geometric isomerization from cis- to trans-structure.
Like most femmes who are cis women, I contend with femme invisibility.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com