They can build server farms in Europe to circumvent the concerns over transferring data to the U.S., as Microsoft just did.
Conversely, ginkgotoxin-induced seizures do not involve the binding to neurotransmitter receptors or ion channels, circumventing the concern for the competition between seizure-inducing agents and tested compounds.
The emergence of iPS cell technology has boosted tremendous enthusiasm for regenerative medicine as these cells reprogrammed from a patient's own somatic cells could, in principle, circumvent the ethical concerns and problem of immune rejection associated with human ES cells [ 27– 327.
The prognostic signature does not contain ER, ER-responsive genes or HER2 and therefore circumvents the expressed concern that expression signatures should provide information independent of these valuable and routinely tested IHC markers.
To circumvent these concerns, in the present study, we addressed the question of whether top-down knowledge can improve visual search in a task in which there was competition between two popping-out elements.
Manipulating sclerostin appears to circumvent this concern because it is produced by osteocytes and therefore potentially restricts the target to bone, although the extent to which sclerostin circulates could be a potential unknown issue that will need to be resolved.
There is, however, an alternative approach to circumvent this concern.
In order to circumvent this concern and bring factor 1 to a homozygote state, we generated trans-heterozygote males from two independently raised P[w+] stocks, i.e., males from P32 recombinant lines were crossed to females from P45.6 (named the tester stock), and the male offspring with this combination of P-inserts (dark-red eyes) were selected for fertility tests.
This feat would ultimately circumvent the biggest ethical concerns surrounding therapeutic cloning – the creation and destruction of a human embryo.
By appealing to the theory of semiparametrics, we are led naturally to a characterization of all treatment effect estimators and to principled, practically feasible methods for covariate adjustment that yield the desired gains in efficiency and that allow covariate relationships to be identified and exploited while circumventing the usual concerns.
In this respect, the development of integration deficient lentiviral vectors circumvents the safety concerns relative to insertional mutagenesis and might pave the way for clinical applications in which gene transfer is targeted to non-dividing cells.
