Again, this could be circumvented by selectively targeting expression with a muscle-specific promoter [ 37].
However… if a system allows encryption to be selectively circumvented at the command of an intelligence agency, it's not really end-to-end encryption in a meaningful sense!" One possibility for enabling 'exceptional access' that has sometimes been suggested is a NOBUS: aka a 'nobody but us' backdoor — i.e. a backdoor which is mathematically/computationally impossible to find.
One possible strategy to circumvent the poor selectivity of the quinols for T. brucei over MRC5 cells is to selectively target them to the trypanosome.
To circumvent these problems, we generated mice selectively lacking IR in chondrocytes through cross-breeding of the mouse strain carrying the IR-floxed allele and the mouse strain carrying Cre recombinase under the control of collagen type II promoter.
This approach allows us to target selectively injured axons and circumvents the early embryonic lethality of Ndel1 null mice.
Here and in the experiments that follow, we removed TagSpoIIE from SpoIIE in cells that were wild type for ftsH to selectively block SpoIIE degradation and circumvent off-target effects from other FtsH substrates had we used an ftsH mutation.
Selectively overexpressing cardiac LXRα in mice circumvented these confounding factors and afforded a system for delineating the heart-specific effects of LXRα.
In this context, alternative non-internalizing ADCs and prodrugs have been developed to circumvent these limitations, in which the drug can be selectively released by an extracellular stimulus in the tumor microenvironment.
To circumvent this problem, the authors used an ethyl chloroformate activated form of myristoic acid that selectively reacted with ADP or ATP in good yields (Scheme 174).
China Inc. has been gaming the rules-based trading system by surreptitiously subsidizing and dumping its exports, selectively blocking trade in strategic goods, systematically stealing intellectual property and cleverly circumventing rules of origin.
To circumvent these limitations, smooth muscle rescue mice were generated, in which PKG I expression is restored selectively in smooth muscle, but not in other cell types of PKG I null mice [ 49].
