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To circumvent difficulty in classifying RNA helicases, we performed a BLASTp search against five model species and trypanosomes with all putative helicases in order to predict their functions.
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It allows us to circumvent difficulties stemming from the fact that the evolution does not improve the qualitative regularity of the initial data.
PBRs have recently been proposed for CLC as an alternative for an interconnected fluidized bed reactors system operated at high pressure, to circumvent difficulties associated with solids circulation and gas/solid separation at high temperature and pressure.
Therefore, neural networks can be used to circumvent difficulties associated with formulating and solving the highly non-linear Nernst Planck equation to calculate solute removal from multi-component solutions at high recovery.
Therefore, to address the role of various signaling pathways simultaneously and to circumvent difficulties posed by the potential for indirect interactions, we created a mutant of BCR-ABL with a tyrosine to phenylalanine mutation at amino acid 177 (Y177F), an SH2 domain deletion (ΔSH2) and a deletion of the C-terminal proline-rich region (ΔPro).
Photoreceptor replacement would circumvent difficulties associated with gene-based therapy and could potentially be applied to RDDs with genetic causes and even at an advanced stage of disease.
Until then, only mtDNA sequences were available from Neandertals, largely because mtDNA occurs in multiple copies per cell, which helps circumvent difficulties extracting DNA from ancient remains.
To circumvent difficulties with respect to the time bias (Anderson et al, 1983), the association between tumour response (partial or complete) and survival was assessed only in patients who survived 4 months after the start of treatment.
In order to circumvent difficulties associated with personal disclosure, participants were also asked the open-ended question: 'In your community, what sorts of things might put people off having a test to prevent bowel cancer'.
Students who did not express confidence in their ability to circumvent difficulties associated with care delivery, who evaluated care delivery negatively and who felt less normative pressure from colleagues at the faculty and less moral obligations to act were less likely to have strong intentions.
Alternative routes need to be developed to circumvent this difficulty.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com