Sentence examples for circumvent death from inspiring English sources

Cancer cells acquire survival mechanisms, such as the inactivation of the p53 gene family (Wyllie et al, 1999), allowing them to circumvent death as a consequence of DNA damage.

Centrosome clustering not only circumvents death but also promotes low-grade chromosome missegregation, which may drive tumor evolution.

Because Nrf2 improves cellular survival under cytotoxic challenges, cells heavily rely on Nrf2 activation to circumvent cell death.

C2 cells therefore seem to actively respond to KIT inhibition with an alternative quantitative and qualitative gene expression pattern to circumvent cell death.

One of such mechanisms, anoikis resistance, plays a pivotal role in enabling metastasis by allowing cancer cells to circumvent cell death induced by lack of attachment.

Her wording is sort of extraordinary, insofar as it circumvents evoking death directly — "the taking of the bird".

Anoikis resistant tumor cells have circumvented the death signals generated by the lack of attachment affording them increased survival times while migrating to secondary sites.

These include self-sufficiency in growth signals, insensitivity to growth suppressors, circumventing cell death mechanisms, limitless replicative potential, sustained angiogenesis, and tissue invasion and metastasis [ 1].

This effect of BPA in circumventing cell death was most prominent at 100 nM rapamycin, a concentration at which the apoptotic ratio of drug-treated versus untreated control was >2-fold in the absence of prior BPA exposure.

Malignant cells must circumvent endogenous cell death pathways to survive and develop into cancers.

To circumvent this perinatal death problem, we have employed the developing mouse retina as a model to further analyze the in vivo function of Top2b.