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In breast cells during lactation, low calcium levels in the circulation trigger secretion of Parathyroid Hormone Related Peptide (PTHrP) to increase osteoclast differentiation and bone resorption, which elevates circulating calcium levels for milk production [46].
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Broecker theorized that changes in the thermohaline circulation triggered dramatic changes in the North Atlantic during the last ice age.
Knorr, G. & Lohmann, G. Rapid transitions in the Atlantic thermohaline circulation triggered by global warming and meltwater during the last deglaciation.
Increased intestinal permeability enhances bacterial and endotoxin translocation from the intestinal tract to the systemic circulation, triggering a systemic inflammatory response (Xu et al. 1997).
With more information, scientists will be able to figure out if global warming will interfere with the ability of oceans to absorb and release heat, destabilize their delicately balanced circulation and trigger dramatic climate changes.
In particular, entry of prostaglandins into the systemic circulation can trigger throbbing headache, nausea, and vomiting [74].
Extracorporeal circulation may trigger an extensive inflammatory response and the release of cytokines, which can induce myocardial ischemia.
Recently, it was suggested that von Willebrand factor abnormalities induced by extracorporeal circulation could trigger acquired von Willebrand syndrome and could explain, at least in part, the elevated bleeding rate in these patients [ 6].
Younger stratal packaging patterns and sequences are rather driven by the ocean circulation which triggers erosion and redistribution of sediments by currents.
One likely possibility is that iron flow from the placental stores into the fetus resulted in higher than normal iron levels in the fetal circulation, thus triggering fetal liver HAMP mRNA expression [68].
The externalised PS binds to tissue factor in blood circulation and triggers the coagulation cascade [ 48, 49].
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