Another possibility is that human antibiotic use has promoted the circulation of resistance genes to other species.Until recently, most of the studies that have looked at bacteria in such species have concentrated on domestic animals.
Though anticipated because of the circulation of blaVIM genes in several other gram-negative species in Europe and the ability of Acinetobacter spp. to acquire foreign DNA, this evolution is worrisome.
Gene segments from G1P[8] strains isolated before and after vaccine introduction were sometimes also found to be closely related, indicating a prolonged circulation of a gene variant for an extended period of time (supplementary fig. S2, Supplementary Material online).
The team theorised that if the circulation of antibiotic-resistance genes was a natural phenomenon, they would find these genes even in this isolated population.
The nucleotide sequence alignment of the 391-bp segment of the 17-kDa protein gene showed that the products were identical to each other and to the R. felis 17-kDa gene, confirming circulation of R. felis in Brazil.
The finding, reported in tomorrow's Circulation, raises the prospect of gene therapy that could help people who've had coronary bypass surgery avoid a second operation.
Furthermore, to exclude any adverse effect of blood circulation on the defects of gene expression in erythroid cells in both ribosomal mutation models, we injected rhodamine fluorescent dye into heart and analyzed the status of circulation at 3 dpf.
Across the 4 sampling periods, the circulation of isolates possessing the mef(A) gene gradually disappeared.
