Suggestions(1)
Exact(30)
Whereas the protective role in CVD is due to both the lower glycaemic index of high fibre foods leading to a better insulin sensitivity, and the reduction in blood cholesterol exerted by fibre in foods through their effect on the enterohepatic circulation of bile acids.
The intracellular ileal lipid binding proteins (ILBPs) are involved in the transport and enterohepatic circulation of bile acids.
In contrast, neither loss of FXR nor interruption of enterohepatic circulation of bile acids affected food entrainment.
Further experiments are needed to elucidate the enterohepatic circulation of bile acids as well as the absorption of dietary sterols in the hyperlipidemic apoE KO model in more detail.
(B) Circulation of bile acids.
Chronic alcohol exposure also alters the enterohepatic circulation of bile acids.
Similar(29)
Enterohepatic circulation enables 95% of bile acids to be reabsorbed from the distal ileum and transported back to the liver via the portal circulation.
The BA enterohepatic circulation and the process of bile formation are tightly regulated, depending on modulating dietary and hormonal signals.
Moreover, LSG increased malabsorption due to loss in energy-rich faecal substrates and impairment of bile acid circulation.
Thus, FXR activation serves as a critical modulator of the enterohepatic circulation and de novo synthesis of bile acids to provide tight regulation of the bile acid pool (2).
Partitioning of bile acids in portal circulation and systemic circulation is dependent on the percentage of hepatic uptake [55] mediated by NTCP.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com