Identification of the repertoire of proteins that are cleaved from the cell surface and of proteins that are otherwise released into the extracellular compartment can contribute to our understanding of tumor behavior, to the identification of potential diagnostic markers detectable in circulation and of potential imaging and therapeutic targets that remain displayed on the cell surface.
This review summarises the different approaches for detecting tumour-associated nucleic acids in the circulation and their potential applications as tumour markers.
In this review, different approaches for detecting tumour-associated nucleic acids in the circulation and their potential applications as tumour markers are discussed.
Dwindling circulation, red ink and potential antitrust concerns more or less forced Hearst to sell, and The Examiner had been on the block since last summer.
Physicians in Greece, as in other Mediterranean countries, should be aware of the circulation of phleboviruses and potential risk for phlebovirus-associated infections during the summer.
Recently, it was reported that TTR has the potential for translocation across the placenta into the fetal circulation and represents a potential shuttle system for thyroid hormones and for exogenous compounds (Mortimer et al. 2012).
As a prism to view one of the most intensively covered news stories of the last few decades, the paper has visibility abroad that overshadows its circulation and limited profit potential.
It stated that "The Manchester Guardian will commence its course with a very considerable circulation" and it assured potential advertisers that it would offer them "a most eligible medium for giving extensive publicity to their notices".
The present study demonstrates the successful production and mid-term application of an autologous, fibrin-based small-calibre vascular graft in the arterial circulation, and highlights the potential for the creation of autologous implantable arterial grafts in a number of settings.
In recent years, the area of circulation and the epidemic potential of CHIKV have increased, and CHIKV has emerged as a major public health problem.
