For the time period studied, an examination of the WHO data shows that the main circulating strain was serogroup A, although serogroup W135 co-circulated [33, Table S8].
But laboratory analysis has shown that the circulating strain of the virus is "very much the same" as last year and has not shown "any significant change", according to the HPA.
And knowing which mutations lead to transmissibility should help scientists all over the world who monitor bird flu to recognize if and when a circulating strain starts to develop pandemic potential.
The season 2011 2012 was not included, since influenza A(H3N2) was the predominant circulating strain.
Low-cost manufacture of poultry vaccine matched quickly to the ever-changing circulating strain is needed for effective vaccination.
In a preliminary test of the medicine against the circulating strain, said Kobinger, ZMapp "performed as well if not better" than it did on the version of the virus found earlier in Zaire.
Complication risk may also be elevated in pandemic scenarios with a more virulent circulating strain.
Comparison of VE estimates with vaccine and circulating strain matches across the years did not reveal any significant differences.
The targeted epitopes from the vaccine may not have matched the epitopes in the circulating strain in this case.
In this study, we constructed an infectious DNA clone CRF33_01B that is a major circulating strain in Malaysia.
The efficacy of a control policy will also depend on the circulating strain, especially in successive waves since individuals infected in previous waves will have acquired some immunity.
