Exact(8)
The circulating species and their clinical impact were not described in Argentina.
The toxicology and efficacy of both parent drug and metabolite need to be assessed in cases such as iododeoxydoxorubicin, in which the parent molecule is the dominant circulating species in mice, but patients have more than 10-fold greater exposure to the metabolite compared with the parent.
We do not know and likely cannot reconstruct the actual evolutionary steps that created the complex phylogeny relationships in this genomic region, or the nature of the ancestors of currently circulating species A and C rhinoviruses.
It is known that the circulating species and serotypes may be considered a marker of the socio-economic climate in an individual setting [ 15].
Both blood cell-derived [ 11, 22] and circulating species were selected to assess miRNA recovery.> -wrap-foot> a miRBase release 21 nomenclature.
The dynamics of four As circulating species in body compartments (arsenates, arsenites, and the As metabolites MMA and DMA) were captured using this PBPK model.
Similar(52)
Development of assays to measure circulating MGP species enabled the investigation of these species in the circulation (11).
Effective influenza surveillance requires new methods capable of rapid and inexpensive genomic analysis of evolving viral species for pandemic preparedness, to understand the evolution of circulating viral species, and for vaccine strain selection.
The effects a circulating patent species may have on liver-stage or sub-patent blood-stage infection by other species remains unclear.
Once we found that there were indeed intact circulating mRNA species in plasma, we went on to establish that organ injury is associated with unique transcriptome profiles.
Models assist to quantitatively relate parent and metabolite concentrations to adverse electrocardiographic effects, including an apparent delay between effect and circulating parent species concentration.
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