Sentence examples for circulating life from inspiring English sources

If the number of teeth in a drive gear is z, failure of any tooth will cause the test to stop, and the circulating life is recorded.

O-blocked doxorubicin prodrug with PEG20k as carrier was selected for further in vivo assessments and presented longer circulating life in pharmacokinetic experiment.

Given j as the number of "circulating life" obtained during the test, then the failure data of the j teeth and censoring data of the j z − 1) teeth can be obtained.

We have recently shown that caplostatin, an HPMA copolymer conjugate of TNP-470 prolonged the circulating life of the drug, increased the accumulation of the drug in angiogenic tissue through the enhanced permeability and retention (EPR) effect [19] and prevented it from crossing the blood brain barrier (BBB), therefore abrogating neurotoxicity [13], [20], [21].

Covalent attachment of PEG can prolong the circulating life and diminish the immunogenicity of proteins [ 9- 11].

That PEGylation prolongs the circulating life of proteins is well documented, but it usually does not completely abolish their immunogenicity.

Hence, the autoimmune disorder that previously manifested in mice lacking Bim appears to depend upon genetic background, even when Bad is also absent, and genetic background may well also have contributed to the low-penetrance lymphoid malignancy reported for aged Bad-deficient mice. 10 The Bcl-2 family governs the circulating life-span of platelets.

Human blood contains a big variety of natural antibodies, circulating throughout life at constant concentration.

In the immune system and also for many therapeutic antibody applications, the Fc region recruits receptors and cell types that maintain the circulating half life of unbound antibodies.

For many therapeutic applications, although retention of the circulating half life of the antibody is crucial, recruitment of effector functions is not necessary.

Once in the blood, neutrophils are short-living cells with a circulating half life of 6 8 h.