Exact(3)
This argues that there is not simply a change of function of antigen-specific T cells, but also a reduction in the circulating frequency of reactive T cells.
Proliferation occurs when the lineage is of minimal susceptibility to the adaptive immune responses of the host population, and a regression in circulating frequency occurs as the host population is increasingly exposed.
Thus, the aforementioned increase in the circulating frequency of CD56DIM NK cells that occurs with age (Almeida-Oliveira et al., 2011; Lutz et al., 2011; Hazeldine et al., 2012)) may represent a compensatory mechanism that counteracts the age-associated decrease in NKCC at the single cell level (Mocchegiani and Malavolta, 2004).
Similar(57)
Switching of the predominantly circulating subtype (HRSV) or genotype (HMPV) may be a result of fluctuating circulating frequencies of contemporary clades, which cycle through proliferative and eclipse phases, and is not due to novel lineage emergence events.
In healthy humans, a correlation was reported between circulating Th17 frequency and BAFF levels as well as switched-memory B cells [ 52].
Interestingly, we observed that whereas RA-a patients show an increased frequency of circulating plasmablasts, the frequency of circulating plasmablasts in RA-r was not different from controls.
The coupled inductors in paralleled inverters are applied to restrain the high frequency circulating current on J-TEXT Tokamak.
A previous study indicated that increased recovery of isolates led to detection of PFGE subtypes circulating at low frequency (25 ).
Where enteroviruses are circulating with high frequency, poliomyelitis manifests as "infantile paralysis," and infection often takes place in babies aged 6 12 months.
In contrast, our results showed a significant increase in circulating Th17 cell frequencies in non-responders.
However, because the majority of the bacterial isolates described in these studies are not recent, some of these genotypes may now be circulating at higher frequencies.
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