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The first task facing the Americans was the adoption of an entirely new set of signals, radio codes, and cipher methods.
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Since the TI CC430 μC supports an AES accelerator module to perform AES128 encryption and decryption in hardware [17], AES128 cipher method was chosen for data encryption.
The present Hitting-Time-based method with the flowchart illustrated in Figure 1 is called CIPHER-HIT, as a continuation of our CIPHER method [ 2].
The CIPHER method scores the candidate genes using a regression model of phenotype similarity and gene closeness in a network [ 16].
The CIPHER method [ 2] and the random walk with restart method (RWR) [ 3, 4] are the approaches which reflect the global structural information of the phenotype-gene heterogeneous network, while the parameters such as the restart rate in RWR, which are related to the performance, are required to be pre-set.
Learn the square cipher method.
One-time pad (OTP) is a principle of key generation applied to the stream ciphering method which offers total privacy.
A novel stream ciphering method based on the Linear Feedback Shift Register (LFSR) with high throughput is incorporated to generate random error vectors, so that a large number of vectors with very good cryptographic properties can be made available with simple hardware.
Recently, after establishing a disease gene prediction method CIPHER and a drug target prediction method drugCIPHER, we further developed a Bayesian partition method named comCIPHER to identify drug-gene-disease co-modules underlying the gene closeness data.
Thus, our CIPHER-HIT method is further used to identify the sub-groups of genes corresponding to the cancer subtypes.
And the CIPHER-HIT method could serve as an important complementarity to current approaches for identification of cancer subtypes.
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