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To add to the challenge, ageing is no longer an orderly chronological process; anarchy rules.
First, it is a chronological process that implies physical decay, but it also appears as a force that otherwise modifies the individual.
It would need to be a chronological process.
The frequency and chronological process of genetic mutations underlying sporadic cancer (adenoma-carcinoma sequence) and UC-associated carcinogenesis are different.
A chronological process typically begins with an individual having a fragmented understanding of his/her illness and its self-management.
The chronological process tends to focus on knowledge of one's condition, learning how to self-manage one's condition and developing expertise regarding one's condition (e.g., [ 29, 31, 34]).
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The characterisation of the chronological failure process and deformation analysis is supported by high speed camera system and Digital Image Correlation.
It is possible that RP gene expressions change along the chronological ageing process, and they are more expressed at day 2.5 in mutants compared the wild type.
As compared with their Caucasian counterparts, where sun-induced damage represents approximately 80% of aging signs in sun-seeking subjects, all facial signs of Asian women studied seem to present a sun-related origin, in addition to the chronological aging process.
We made the very surprising observation that early during the chronological aging process and significantly before cell death sets in, yeast cells undergo an abrupt loss in redox homeostasis as indicated by the massive oxidation of the large majority of thiol-containing cytosolic, nuclear, and mitochondrial proteins.
Reactive oxygen species (ROS) homeostasis plays an important role in chronological aging processes and some degenerative diseases [1] [5].
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