Footage of the Queen edited in non-chronological order caused the Crowngate controversy in 2007.
Calorie restriction (CR), which resembles the starvation conditions used to assess chronological life span, causes longevity extension in all the ageing model systems.
Furthermore, it was recently reported that chronological aging is caused by toxic effects of acetic acid that accumulate in the medium of stationary phase cultures.
Different tooth germs are at different stages of development at any one time point and therefore a substantial disruption, e.g. a major environmental insult, over a defined chronological period may cause different defects in different teeth depending on the developmental stage of the individual tooth germ.
We used a set of complex detection rules to take account of the patient's clinical and biological context and the chronological relationship between the causes and the expected outcome.
Burtner et al. [ 12] recently proposed that the primary cause of chronological aging in budding yeast is toxic effects of acetic acid that are not caused by oxidative stress, and that inactivation of Sch9 or Ras2 protect against acetic acid toxicity through unknown mechanisms rather than reduced growth signaling.
The conflicting views on the subject may be caused by chronological uncertainties and ambiguities in the interpretation of different climate proxies measured in different sedimentary sequences.
Two independent genetic screens using this barcode-tagged deletion mutant set have identified many genes whose deletion caused lengthened chronological lifespan as detected by an increase in the abundance of the long-lived mutant barcodes [ 8, 9].
In one model developed by Fabrizio and Valter Longo [ 16] as well as by Matt Kaeberlein and Brian K. Kennedy [ 17], yeast chronological senescence (CS) is caused by acidosis due to overproduction of acetic acid.
The accumulation of extrachromosomal rDNA circles (ERCs), a sign of rDNA instability, is suggested to be a cause of replicative aging in yeast (Sinclair and Guarente 1997), whilst acetic acid accumulation in the medium is considered to be the primary cause of chronological aging in yeast (Burtner et al. 2009).
