Sentence examples for chronological alteration from inspiring English sources

In addition, the intra-tumor distribution pattern was closely related to the chronological alteration of tumor blood flow as well as vascular permeability in the growing tumor tissue.

To further analyze the chronological alteration in the mutant mice, we examined the peripheral and CNS mainly with morphological approaches, such as electron microscopy and immunohistochemistry. Accordingly with the sensory dysfunction, neural degeneration, glial proliferation and synaptic remodeling in the dorsal horn of the spinal cord were found in adult mice.

Thus, documentation of the chronological alteration in the morphology of neuromuscular junctions (NMJs) and of organelles was possible.

It is characterized by chronological alteration of intracellular biochemical signaling pathways followed by cellular morphological changes, DNA fragmentation, perturbation of mitochondrial membrane function and changes in the plasma membrane [ 27].

Based on the integration of K Ar geochronology and remote sensing methods, a new map is presented for Al-Lajat plateau volcanic field, and a chronological model for alteration processes (such as weathering) in relation to Quaternary paleoclimatic changes.

Due to these unique properties, urothelial tumours provide a good model for the clonal analysis and chronological tracing of genetic alterations in human cancer.

Our aims were to i) verify the occurrence of TSG hypermethylation in an independent tumor series; ii) assess the temporal relation of methylation to tumor development; iii) determine the chronological relation to genetic alterations; iv) evaluate the relation to mutations in predisposing genes; and v) assess associations to metastatic disease.

Temporal sequence error* 1 point per each alteration in the chronological order of events.

Chronological skin aging results in physiological alterations of keratinocytes and epidermal functions that contribute to epidermal thinning or atrophy, and barrier dysfunction, delayed wound repair, as well as increased susceptibility to pathologies including ulceration, dermatitis, and eczema [ 4, 60, 62].

The possibility that alterations in the Rim15-dependent G1 arrest induced by nutrient deprivation impact chronological lifespan when nutrient signaling pathways are altered has not been investigated previously.

Most efforts to understand how alterations in nutrient-signaling pathways impact chronological lifespan in budding yeast have focused on changes in nutrient depletion-induced stress resistance, especially resistance to oxidative stress.