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Multiple mechanisms of insulin signaling pathway impairment have been described in obese individuals, involving complex interactions of chronically elevated inflammatory mediators, adipokines, and the critical role of the endoplasmic reticulum (ER) stress-dependent unfolded protein response (UPR).
He is chronically fickle.
Much unfolded from there.
The romance quickly unfolded.
Here is what unfolded.
b) an unfolded word.
Then, something unexpected unfolded.
It all unfolded quickly".
I'm chronically sorry.
Here is how it unfolded.
I became chronically ill.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com