Sentence examples for chronically decreased from inspiring English sources

In pickwickian syndrome the rate of breathing is chronically decreased below the normal level.

IR induced a dose-dependent effect on myocytes' systolic function with acutely increased, but chronically decreased Ca transient amplitudes, which was associated with an acutely unaltered but chronically decreased sarcoplasmic reticulum (SR) Ca load.

PLN phosphorylation in HF is chronically decreased (PLN hypophosphorylation) which may directly contribute to depressed SR Ca2+ uptake [ 61].

Indeed, beside chronically decreased glycaemia (supported by decreased HbA1c values), we observed after sacrifice that fasting plasma NEFA concentrations in the SA15% group were decreased by ∼20%.

To investigate if these chronically decreased ECF glucose baseline concentrations in the TG arcAβ mice were indeed caused by insufficient blood-to-brain glucose uptake due to decreased GLUT1 expression, glucose uptake was assessed (Fig.  2c).

Chronically decreased HRV has been used to predict an increased risk of cardiovascular morbidity and mortality (Kleiger et al. 1987; Lahiri et al. 2008; Tsuji et al. 1996), and several studies suggest that the intake of n-3 FA may improve autonomic function, including an increase in vagal activity and baroreflex sensitivity (Mozaffarian et al. 2008; O'Keefe et al. 2006).

117, 118 Exendin-4 and liraglutide, two types of GLP-1R agonists, also restored impaired insulin signaling, exerting neuroprotective effects on neurons and synapses, improving cognition, and decreasing Aβ accumulation in the brain in a transgenic mouse model of AD. 75, 119 As recently suggested, an agent that chronically decreases Aβ levels should be beneficial in APOE-ε4 allele carriers.

This idea is consistent with clinical studies that have reported that humans who abuse METH chronically show decreased brain glucose metabolism [84], [85].

Non-molting, chronically stressed birds decreased nighttime heart rate during healing, but this pattern did not exist in molting birds.

This is consistent with preclinical studies showing that exposure to cocaine-cues in chronically treated rats decreased glucose metabolism in limbic regions [26].

The pathophysiological downside of this regulation may occur in diseases such as chronic kidney disease, where PTH and FGF23 are chronically elevated due to decreased renal 1,25(OH)2D production and phosphate retention.