Exact(27)
In addition to the acute and chronic tests, an avoidance response test was applied.
Chronic tests were performed using 150 g DW OECD artificial or LUFA 2.2 standard soil.
With respect to environment, these nanospecific information requirements subject chronic tests instead of acute tests at lower tonnage levels.
The data requirements regarding the submission of acute and chronic tests depend on the tonnage produced [5, 7].
Regarding environmental information, chronic tests instead of acute tests and toxicity to sediment and soil organisms are necessary at lower tonnage thresholds.
Moreover, it can be supposed that some chemicals showing less acute toxicity may address non-lethal endpoints covered by chronic tests.
Similar(33)
Note that in the chronic test [149] a clear effect was observed at the lowest tested concentration (Additional file 1: Table S3), i.e. significant effects may be caused at a lower microplastic level.
Chronic invertebrate tests according or equivalent to OECD 211 (Daphnia chronic test) were considered using the 21 days NOEC [17].
Further research and optimization of the chronic test design are required.
Thus, the study type of the chronic test appeared to have an obvious effect on the ACR.
Effects of Carbo-Iron on H. azteca were determined in a 10-d acute test, a 7-d feeding activity test and a 42-d chronic test.
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