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Clinical experience indicates that Neuroprolotherapy is able to abort chronic cycling migraine, theoretically by repair of the peptidergic sensory TRPV1 receptors via the antagonist effect of 5% dextrose.
Several studies suggest that a significant proportion of patients (between 30 50%) will respond poorly to antidepressants and may develop a chronic, cycling course of illness with more frequent depressive episodes, more suicidal behaviour and, in the longer-term, more treatment-resistance [ 8, 9].
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The long-term health implications resulting from extreme and chronic weight cycling and the associated energy restricted lifestyle of a professional jockey remain unknown.
Diagnosis of bipolar disorder (BPD) in preschool children is controversial, although preliminary data suggest that children with BPD may present with classic manic symptoms in a more chronic, rapid cycling presentation.
For irritability or elevated mood to count as a symptom of BP, it must appear in distinct and sustained episodes--not as chronic or rapidly cycling.
Additional information from a recent large, multicenter, retrospective study indicates that patients diagnosed with JIA experience a chronic course involving cycling of disease between active and inactive states over the course of years.
Clinically, the course of illness in lamotrigine responders was rapid cycling or chronic, while episodic in responders to lithium, and lamotrigine responders had higher co-morbidity of panic disorder and substance abuse compared with lithium responders.
Although, the association and localization of IL-33-producing SEMFs with mucosal ulcerations suggests an important role in wound healing, one cannot rule out its potential role in gut-associated fibrosis, particularly in the setting of cycling of chronic tissue damage and repair, characteristic of IBD.
A group led by Alon [ 33] treated 10 chronic stroke subjects with motorized cycling.
Doctors were creative with their diagnoses – one writing in 1897 claimed cases of women suffering chronic dysentery as a result of cycling – but one of the more common concerns was that women might exhaust themselves with too much exercise.
Chronic diseases are often associated with cycling in and out of treatment.
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