In order to further probe the mechanisms by which receptor down-regulation occurs, we took advantage of the different concentration-dependencies of palonosetron and ondansetron for producing acute and chronic receptor inhibition (competition and down-regulation, respectively, Figure 6A,B).
9 10 11 12 13 14 15 16 22 23 24 Biological vulnerability for adverse outcomes among younger mothers may also persist through physical immaturity 16 19 and exacerbation of the effect of chronic malnutrition by competition for scarce nutrients between the mother and fetus.
For Westernized men from areas with a high intensity of male male aggression and competition, the chronic nature of challenges may support chronically elevated levels of testosterone.
Workers across Europe may have to become accustomed to longer hours as many countries face chronic economic stagnation, increased competition and continuing high unemployment.
Michel Franco is the Mexican director who made the savagely confrontational high-school bullying drama After Lucia; now, he comes to the Cannes competition with Chronic — a sombre, intelligent, finely composed study of one man's emotional endgame.
Susan Dentzer Editor in Chief, Health Affairs Bethesda, Md., March 24 , 2009 To the Editor: Chronic diseases, not lack of competition in the marketplace, are the real threat to Medicare's long-term survival.
The prospect of First Division representation in next month's final is hardly filling the organisers with undiluted joy at a time when the troubled competition is in chronic need of an image overhaul.
Rafael Nadal withdrew from the United States Open on Wednesday, saying he was not ready to return to competition because of chronic knee problems that forced him out of the Olympics and two warm-up tournaments for the Open.
As Apple's market power grows, its ideology is destined to bring Apple into chronic conflict with American and European competition laws.
