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Deregulated cyclin E induces chromosome instability.
Differential roles of the RNases H in preventing chromosome instability.
Nicholson, J. M. & Cimini, D. Link between aneuploidy and chromosome instability.
Spruck, C. H., Won, K. A. & Reed, S. I. Deregulated cyclin E induces chromosome instability.
Chromosome instability was highest among spontaneous mutants and decreased with increasing LET.
Shima, N. et al. A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice.
Xu, G. L. et al. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene.
Michel, L. S. et al. MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells.
Indeed, many of the germ-line variants were in genes related to DNA repair, microsatellite instability, and chromosome instability.
Germline mutations that inactivate BRCA2 promote early-onset cancer with chromosome instability.
Cytogenetic analysis revealed high chromosome instability and structural abnormalities confirming the source of cell line from a patient with AML.
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