Sentence examples for cholesterol core from inspiring English sources

One year later, Wang et al. (2006) developed a variation of this previous NP with a hydrophobic cholesterol core, to uptake poorly water soluble drugs, and coated with a cationic polymer shell, to strongly attach to cell membranes, for the co-delivery of paclitaxel and a cytokine, the interleukin 12-encoded plasmid.

Here the primary bile acids, those bile acids that are produced in the liver, are modified by enteric bacteria dehydroxylating the cholesterol core and removing the conjugated amino acid to produce unconjugated secondary bile acids.

A photoaffinity label has also been introduced into one of the cholesterol cores to permit covalent attachment of one of the units into its respective protein-binding pocket.

To further deplete intracellular cholesterol, the core macromolecule structure was exploited to solubilize a hydrophobic small molecule agonist for nuclear Liver-X Receptors, which regulate the efflux of intracellular cholesterol.

LDL is a complex nanoparticle with a cholesterol ether core enveloped by phospholipids, non-esterified cholesterol and apolipoprotein B100.

In later stages, AS plaques exhibit a necrotic core, cholesterol clefts and calcifications [ 119].

Among the 72 patients with high LDL cholesterol values at core study baseline, 22 patients (30.6%) had normal LDL cholesterol values at extension study LOCF endpoint.

While NPC1, RFBP and FRα bury their respective ligands in the protein core (cholesterol in NPC1, riboflavin in RFBP and folate in FRα) with the help of extensive protrusions from the core CRD fold (shown in gray in Figure 5F H), Fz8, the closest structural homolog of the zSmo CRD structure, binds the palmitoleyl moiety covalently linked to Wnt proteins in a shallow groove.

Similar to LDL-C, cholesterol-enriched lipid core in Lp(a) plays a crucial role in atherogenesis and progression.

The lipid droplet essentially consists of a hydrophobic neutral lipid core (containing cholesterol esters and tri-acyl glycerol) surrounded by a single monolayer of phospholipids rather than the phospholipid bilayer normally found enveloping organelles.

After the full period of HFC and enzyme infusion, significant advanced lesions developed within the aortic branching vessels studied, i.e. innominate- (early start) and left subclavian artery (later start) with intimal thickening, cholesterol accumulation and necrotic cores in both hyaluronidase group (figures 1 and 2A).