Sentence examples for cholesterol biosynthesis from inspiring English sources

How is cholesterol biosynthesis affected?

Cholesterol biosynthesis can be divided into four stages.

Liver-specific microRNA miR-122, on the other hand, enhances cholesterol biosynthesis by an unknown mechanism.

The top down-regulated genes were involved in cholesterol biosynthesis pathways, where the expression of genes encoding two key enzymes in cholesterol biosynthesis DHCR7 and DHCR24 were down-regulated 7.5- and 10-fold respectively.

NB-598 potently suppressed de novo cholesterol biosynthesis with a measured IC50 of 76 nM (Fig. 2b).

& Steinberg, D. Uptake and degradation of low density lipoprotein by swine arterial smooth muscle cells with inhibition of cholesterol biosynthesis.

As expected, NB-598.ia did not show any effects on de novo cholesterol biosynthesis (Fig. 2b).

The insulin-induced gene 1 protein (Insig1) inhibits the cholesterol biosynthesis pathway by retaining transcription factor SREBP in the endoplasmic reticulum, and by causing the degradation of HMGCR, the rate-limiting enzyme in cholesterol biosynthesis.

25:9932-9939.Another fairly technical article describing the research behind discoveries relating to cholesterol biosynthesis disruption.

Further, BF102 also inhibits cholesterol biosynthesis by suppressing HMG-CoA reductase gene expression in hepatocytes.

The results affirm the role of Hsd17b7 in the cholesterol biosynthesis pathway in mammals.