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In conclusion, our data show that no first choice protocol seems to be adopted in clinical practice for the treatment of obesity-related hypertension.
Rats were trained to consume ethanol using the intermittent-access two-bottle choice protocol for 10 weeks.
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Examples of PC (sometimes called "forced choice") protocols can be found in [1 3].
We chose to use mice naïve to the experimental arena because although habituation is used in some light/dark choice protocols [72] this can reduce the amount of time spent in the dark [73] which may mask subtle light responses.
In either case, our key prediction is that using choice protocols where all consequences are learned from experience should lead to similar choice patterns across species.
Since in most inter-temporal choice protocols the effects of delay are confounded by the effects of reinforcer size [37], inter-temporal choice protocols that distinguish between the effects of delay and magnitude of reinforcement [37] are of particular interest in attempts to identify the neural underpinnings of delay discounting.
Visual acuity and contrast sensitivity of mice was evaluated from optomotor responses using a two-alternative forced-choice protocol (Umino et al., 2008; Kolesnikov et al., 2011).
The ISI between the two pulses was modified based on subject response with a 1 up/1 down forced-choice protocol for the first 10 trials and responses for the remaining trials of the run were tracked with a 2 up/1 down forced-choice tracking protocol in which two correct subject responses resulted in a decrement in the ISI.
This study demonstrated that it is possible to modify the proportion of judges choosing the no-difference option through ballot design, and that free-choice protocols may show much higher discriminative power than forced-choice tests when the no-difference alternative is properly used.
Because data with regard to implementation of these recommendations are lacking, we surveyed diagnostic laboratories in Tennessee about their protocols for STEC detection and identified factors influencing their choice of protocol.
There is no preferred choice of protocol that gives the optimal QoS, as there are pros and cons for each specific protocol.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com