Sentence examples for choice of challenge from inspiring English sources

With many promising new blood-stage vaccine candidates entering the clinical phase, careful consideration needs to be given to the choice of challenge model employed to assess efficacy prior to field studies, including which effector mechanisms may contribute to protective immunity and whether these may also be effective against the liver stage.

Under the plan, a manager would have the choice of challenging or not challenging a call; arguing on the field would not be tolerated.

The lack of the Augusta National course is disappointing, only partially compensated by the enhanced visuals, but the thrill of growing your own PGA pro remains, along with an albeit limited choice of challenges and online modes.

A key issue was the choice of challenging propositions whilst minimizing the possible subjectivity during this phase.

These data have important implications for the choice of clinical challenge model used to assess new candidate blood-stage malaria vaccines and demonstrate that the induction of effective immune responses against both the liver and blood stages of malaria infection can lead to increased vaccine efficacy.

Strangely, the one place where the show could have benefited most from hewing closely to the "Top Chef" and "Project Runway" model — in its choice of competitive challenges — was where it deviated.

NETs have great variability in cellular differentiation, which makes the choice of tracer challenging.

A targeted review of relevant serious games precedent and theory is discussed, which informs the specification of three game levels that provide increasing degrees of challenge, choice, collaboration and context.

In the conclave to elect Calixtus' successor, the choice of Honorius was challenged by a faction supporting Cardinal Teobaldo Buccapeco (Antipope Celestine II).

Mr Arafat once more faces the desperate choice of either violently challenging his Islamist dissidents or being stunned by the military solutions Israel has in store for him.

This assumption makes the choice of primary endpoint challenging.