Sentence examples for choice of alignment from inspiring English sources
The choice of alignment tool for each biologist should be tailored to the goals of the sequencing project.
Although sometime it is desired to have different parameters for different applications, the real-valued gap opening and extension scores as well as the choice of alignment methods make it hard to optimize these parameter settings for a certain task.
A quick comparison of the scatterplots for these three datasets shows that the choice of alignment method has little affect on the resulting accuracy and reproducibility for any of the methods.
Likewise, the observed limits of length variation, specific for each domain superfamily would be particularly relevant in the choice of alignment length search filters commonly applied in protein sequence analysis.
We highlight that modeling errors will be influenced by parameterization and choice of alignment software.
Hence, to some unknown degree, our analysis is necessarily biased by the choice of alignment.
Our conclusions hold for all choices of alignment and threshold; here we only present the results based on mammalian conservation with PhastCons score threshold of 0.5.
Since the alignment results may be sensitive to the choice of the alignment score threshold, especially for the lower quality data S2, we explore the impact of this parameter "-t" in Novoalign by setting it at different values: default, 60, 70, and 75.
Our data demonstrate (1) that design of the tibial component restricts the choice of rotational alignment and (2) that ATT is not a reliable landmark for rotation of the tibial component.
The choice of the alignment program depends on the biological application and on the type of sequencing technology used to generate the data.
