Sentence examples similar to chiral inversion rate from inspiring English sources

A fitted model to predict the chiral inversion ratio of R-salbutamol was proposed using a Box Behnken design.

Moreover, the calculated results of the fitted model matched very well with the enantioselective pharmacokinetic study of R-salbutamol, and the individual difference of the chiral inversion ratio of R-salbutamol was related to the individual gastric environment.

In the present study, pure enantiomers were not administered and chiral inversion and the inversion rate could not be determined.

77 Esomeprazole is highly protein-bound in plasma and has a high chiral stability with a very low inversion rate to the R-isomer at 0.4%.

The chiral inversion has been a concerned issue during the research and development of a chiral drug.

Chiral inversion of R-salbutamol to S-salbutamol has been detected in urine samples.

The changes in enantiomer composition may also be caused by biologically catalyzed chiral inversion.

No chiral inversion was observed during sample storage, preparation procedure and analysis.

Thus, whereas insulin's core readily accommodates allo-isoleucine at A2, its activity is exquisitely sensitive to chiral inversion.

The results indicated that pH and temperature were two dominant factors that caused the chiral inversion of R-salbutamol, which should be taken into consideration during the analysis of chiral drugs.

In this paper, based on reciprocal chiral substrate specificity, taking achiral molecules, ethanolamine (EA) and malachite green (MG) as two model targets, biostable L- DNA aptamers and L-RNA aptamers were generated respectively by chiral inversion of existing D-aptamers.