Sentence examples for chip domains from inspiring English sources

Interestingly, all CHIP domains were rated within the normal range by the patients.

To identify the CHIP domains that regulate BACE1 stability, a series of CHIP mutants were examined for their abilities to regulate BACE1 stability.

However, we also expected to see some differences, though likely smaller differences, between these two groups on the other CHIP domains because they also measure aspects which could be relevant in discriminating between groups with and without mental health problems.

Co-immunoprecipitation assays showed that isolated CHIP TPR domain binds to the ARM-ANK-LRR domains of LRRK2 but not to the ROC-COR-kinase-WD40 domains of LRRK2 (Supplemental Figure S2A, B).

By contrast, deletion of the CHIP TPR domain did not disrupt the interaction between CHIP and the ROC-COR-kinase-WD40 domains of LRRK2 because these domains robustly co-immunoprecipitated with CHIPΔT (Figure 2F).

Deletion of the CHIP TPR domain completely abolished the interaction between CHIP and the ARM-ANK-LRR domains of LRRK2 based on the absence of co-immunoprecipitation (Figure 2E).

This raises the possibility that the CHIP TPR domain binds to LRRK2 indirectly, via Hsp90.

We further found that isolated CHIP TPR domain binds to full length LRRK2 (Supplemental Figure S2E) and that this was blocked by the K30A point mutation (Supplemental Figure S2F).

The CHIP-AE domains have been introduced as categorical variables.

Those from standard families presented better scores in all the CHIP-AE domains and sub-domains, similar results to the USA studies [ 10, 18].

Standardized mean score differences in the Spanish CHIP-CE/PRF domains were analyzed using the ES [ 21].