Sentence examples for chimera support from inspiring English sources

Thus, both our study and the earlier studies of the Nox1/4 chimera support the idea that the DH domain rather than the TM domain is a major determinant of the overall activity and is the target for regulation by activating subunits.

The relative levels of growth support are consistent with the data presented here (where the topoIIα C-terminal domain chimera supports low levels of growth and the topoIIβ C-terminal domain chimera supports no growth at all), although the levels of growth differ, perhaps because of differences in the experimental systems or the sensitivity of methods [27].

Likewise, more lung nodules were developed in chimeric B6 mice bearing WT-BM than HO-1+/− chimeras, supporting the involvement of hematopoietic HO-1 in this process.

As shown in Figure 1 e,f), the lung metastases developed at 10 days post-B16F10 inoculation were significantly lower in HO-1+/− chimeras compared to WT chimeras, supporting the involvement of hematopoietic HO-1 in facilitating tumor colonization at metastatic sites.

In connection with this concern, we have added data to the figure 7 supplement showing the OTII T cell response in DT-treated Ebi2 -/- :CD11c-DTR mixed BM chimeras, supporting the conclusion that the reduced wild-type T cell response is due to the role of EBI2 in CD11c+ cells, most likely DCs.

These results show that a lack of SECIS element binding does not explain the inability of the SBP2L-SBP2 chimera to support Sec incorporation.

The peptide chimera studies supported recent results on the importance of a mid-region helix for bioactivity of GIP, and confirmed existence of two separable regions with independent intrinsic receptor binding and activation properties.

Second, although ESCs can contribute to chimeras and support full development, not all ESC cultures are able to do so.

Together with our finding that the Vik1head Cik1tail chimera fully supports viability, this implies that the key function of Kar3 in vegetatively growing yeast cells requires motility supported by any of the two non-catalytic heads—and the Cik1 tail domain, but does not involve spindle localization via Bim1.

As a consequence, Britain was forced to divert resources used to fight the war in North America to theaters in the West Indies and Europe, and rely on what turned out to be the chimera of Loyalist support in its North American operations.

The MalF-TM-SpoIIE chimera does not support wild-type sporulation efficiency and we have added these data to the table in Figure 4 source data 1.