Sentence examples for chimera in which from inspiring English sources

We previously described a novel dual inhibitory anti-gp120 aptamer siRNA chimera in which both the aptamer and the siRNA portions have potent anti-HIV activities.

We created an antibody/c-Kit chimera in which the extracellular domain of c-Kit is replaced with an anti-fluorescein single-chain Fv antibody fragment and the extracellular D2 domain of the erythropoietin receptor.

Our nation's rosy myth of resilient homesteaders, the wholesome world of Laura Ingalls Wilder's books, is exposed as a chimera in which people were lured with the promise of "free" land into sacrificing their entire lives — all in a 70-minute work that could be summed up as "The Turn of the Screw" meets Willa Cather, as told by Stephen King.

Additionally, Huh-7 cells constitutively expressing IRNA became refractory to infection by a PV-HCV chimera in which the PV IRES is replaced by the HCV IRES.

To take an extreme, albeit hypothetical, example, the idea of a human/chimp neural chimera in which the human and chimp traits are thoroughly mixed is a chilling one.

Pfa3 INS, the chimera in which Swf1 DHHC domain is replaced by that of Pfa3, is also unable to complement pfa3Δ.

We also engineered tandem repeats of two identical MC159 DEDs, MC159 DEDs in the reverse orientation, and MC159-caspase-8 MC159-caspase-8 MC159-caspase-89 was replachimeras the corresponding DED of caspase-8.

A model of metabolite channeling of this FeIII is tested here by first constructing and kinetically characterizing in Fe-uptake two Fet3p Ftr1p chimeras in which the multicopper oxidase/ferroxidase domain of Fet3p has been fused to the Ftr1p iron permease.

Using an equine arteritis virus (EAV) infectious cDNA clone, we have engineered chimeras in which the ectodomains of the two major envelope proteins, the glycoprotein GP5 and the membrane protein M, were replaced by sequences from envelope proteins of related and unrelated RNA viruses.

In hematopoietic chimeras in which radioresistant cells could not present, via their IL-15 receptor α-chain, IL-15 to developing thymocytes, strongly reduced proportions of Treg developed (Marshall et al., 2014).

In mixed hematopoietic chimeras in which growing numbers of Treg precursors expressed the common cytokine receptor γ-chain ("γc", a constituent of, among others, the receptors for IL-2 and IL-15), the numbers of thymic Treg saturated at approximately 106 cells, suggesting that availability of IL-2 and IL-15 quantitatively controls Treg development (Tai et al., 2013).