Exact(20)
Dipetarudin is a potent direct thrombin inhibitor that was genetically engineered as a chimera between dipetalogastin II and hirudin.
In another study, Piezo1's N-terminal "propeller" domain was proposed to constitute an intrinsic mechanosensitive module based on expression of a chimera between a pore-forming domain of the mechanically insensitive ASIC1 channel and Piezo1 (Zhao et al., 2016).
We engineered a chimera between the motor domain of the kinesin 7 Teandand the globular tail of the myosin V Myo52, which we show transports Ypt3, a myosin cargo receptor, to cell poles along microtubules.
We previously constructed a red light-sensitive Escherichia coli transcription system based on a chimera between the red/far-red switchable cyanobacterial phytochrome Cph1 and the E. coli EnvZ/OmpR two-component signaling pathway.
Also shown in Fig. S1 are the disappointing outcomes of using N-terminal and C-terminal chimera between β2AR and the robustly-expressed M2 receptor.
Since this network shows that there are not sequences in which the branches are connected by two distinct parental lineages, the selected fragment is not a chimera between distinct HIV-1 lineages.
Similar(40)
Capsaicin activation of TRPV1 was first investigated by making chimeras between capsaicin sensitive and insensitive orthologs.
To address this problem, families of detectors that are chimeras between signal transduction proteins and fluorescent proteins have been designed.
A strategy for construction of chimeras between a variety of HAMP domains and the catalytic domain of the AC Rv3645 is described.
Chimeras between member viruses in the family Arteriviridae have also been constructed and utilized to study cell tropism and functional complementation.
Chimeras between AMPA and the related kainate receptors demonstrate that the ligand binding domains alone control the lifetime of the desensitized state.
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