Exact(2)
The existence of a stable single-head interacting intermediate of the chimera before ATP addition was confirmed by titration over a huge range of microtubule concentrations (Figure 4B).
Since we know from the single-channel measurements that the chimera DNA does not affect the single channel conductance (Fig. 3 B), the large increase of peak current after hybridization must be due to a depressed opening probability in the ssChi state (The chimera before hybridizing to any complementary DNA is referred to in the following as the single-stranded chimera (ssChi)).
Similar(57)
Functional pluripotency was confirmed by generation of multiple chimeras before and after Cre excision (Table 1).
Contigs were individually inspected for low-quality sequence, splice variants and chimeras, before ESTs were reassembled.
First, RC-seq reads fully span L1-genome junctions, enabling bioinformatic identification of molecular chimeras before PCR validation.
First, we randomly reassigned (shuffled) miRNA-mRNA pairs found in chimeras, before performing the folding prediction and clustering.
Further studies will be necessary to test the ability of hNCC in vivo to differentiate into functional cells representative of any or all tissue types with a teratoma assay; a better test would be their ability to contribute to chimeras, in particular to the germ line of such chimeras, before claims of pluripotency could be supported.
(4) Denoising and chimera removal: before sequence clustering, denoising and chimera removal are required for 454 and Illumina datasets.
Conversely, blockade of leptin with anti-leptin antibodies or with a soluble mouse leptin receptor chimera, either before or after onset of EAE, ameliorated the clinical symptoms, inhibited antigen-specific T cell proliferation, and switched cytokine secretion toward a Th2 and T regulatory profile [ 76].
To determine whether the reduction in pro-T cells was dependent on the stromal changes, and hence merely correlative with thymic involution, we determined the compartmental control over this trait using the BM chimera approach used before.
Mechanical threshold at the central plantar surface of the hind paw was assessed before the chimera and CFA injections (as a basal pain threshold).
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