This is intriguing because the biological significance of 5hmC has chiefly been explored in the context of embryonic development.
For the next 150 years the river system was explored chiefly to foster the development of transportation.
Gibbs and his colleagues have explored the relationships between structure properties (chiefly the bond lengths) and the topological properties of the electron density.
MacLeod's fiction chiefly examined the lives of the working people of Cape Breton miners, loggers, fishermen, and farmers and sensitively explored family relationships as well as the relationship of the islanders to their Celtic past.
As data collection progressed, 'snowball sampling' was used to recruit additional dentists from groups whose views had not yet been sufficiently explored but where the available sample from the questionnaire respondents had been exhausted (chiefly young female dentists).
Suggested alterations to be explored in the design of new compounds are the placement at the 3′ and 4′ position of the phenyl ring of electron-withdrawing groups that lie chiefly in the plane of the ring, for example, halogen substituents on the 3′,4′-benzo analog, 79.
These two trials [19 21] chiefly tested the value of concomitant chemotherapy and radiotherapy in intermediate rectal cancer, although the European Organisation for Research and Treatment of Cancer (EORTC) trial, having a 2 × 2 design, also explored the value of adjuvant 5-FU/leucovorin.
Former research exploring these changes has chiefly focused on lipid components; fatty acids, wax, esters, triglycerides, cholesterol and squalene within fingerprints, as these tend to decrease significantly in concentration over time (Mong et al. 1999; Weyermann et al. 2011).
First, given that our results show that a marked temporal locality in BitTorrent traffic chiefly influences cache effectiveness, future research should extend our evaluation exploring optimizations in a LRU-based cache.
