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Hugely inadequate infrastructure is one of the chief obstacles in India, as is a business climate famous for its bureaucracy.
But he also hoped to soften the resistance of the Russian Orthodox Church, which views the pope's support for Ukraine's five million Greek Catholics as one of the chief obstacles to reconciliation.
The Boer government of the Transvaal Republic was the chief obstacle to Rhodes's plans for the federation of all South Africa under the British.
For now, the suit's chief obstacles may be political rather than legal.
For days, the chief obstacle to a deal was the design of a mechanism to force the committee to act — or to make sure spending cuts were adopted if the committee failed.
Russia and France are the chief obstacles here.
The Senate filibuster, the health insurance lobby, and Senator Lieberman were our chief obstacles.
Hexose and pentose cofermentation is regarded as one of the chief obstacles impeding economical conversion of lignocellulosic biomass to biofuels.
For our bright, badly off kids, the chief obstacle to higher education is not lack of encouragement or broadening of horizons, it's cash – in terms of day to day getting by and the spectre of future debt.
Unlike Plato's guardians, of course, Garten's mandarins hold no formal responsibility for society, and he recognizes that this is the chief obstacle to his vision.
The chief obstacle to reform is that Kim cannot make the same admission in public without removing the only excuse for not joining up with the capitalist South.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com