In this article, we use the chick model system to provide a global view on how RA influences organ position at different levels along the AP axis.
Besides, a different chick model system by in vivo chick embryonic CAM assay showed that the number of blood vessels gradually decreased with increasing concentrations of ellagic acid accompanied by VEGF stimulation (Fig. 3c).
This study was designed to investigate the effect of in ovo ethanol (EtOH) exposure on retinal development and myelinization of optic nerve fibers at an ultra structural level in a chick embryo model system.
Recent research findings suggest that physiologic amounts of supplemental dietary boron (PSB) affect a wide range of metabolic parameters in the chick and rat model systems.
Therefore, we turned instead to the chick as a model system for canal morphogenesis.
As a result, the more difficult detection of micrometastases becomes an inherent part of the chick embryo CAM model system [ 47].
In "The Chick: A Great Model System Becomes Even Greater," Stern 2 stated: "Now, it has become even more powerful thanks to several new technologies: in vivo electroporation, ES cells, novel methods for transgenesis ….
In addition to insects, this technique should find applications in areas including vertebrate development (in such model systems as zebrafish or chick), and any other field in which the understanding of moving fluids behind opaque anatomy, at small scales, is key to answering outstanding questions of physiology.
Because many different model systems (including amniotes such as the chick and pig) orient their asymmetry without the benefit of cilia (Levin and Palmer, 2007; Spéder et al., 2007; Gros et al., 2009), it is unclear which species is the best model for human disease-relevant symmetry breaking.
Among various animal model systems designed to study the mechanisms underlying angiogenesis, chick embryo models have been useful tools in analyzing the angiogenic potential of purified factors and intact cells.
