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Such a role for fluid dynamics has been demonstrated in early chick heart development [25].
Furthermore, these findings can lead to the assumption that increased sensitivity to β-mimetics detected in the later stages of chick heart development is substantiated by a more efficient coupling of the β-ARs to their downstream effector AC.
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Davis, AM, Izatt, JA, and Rothenberg, FG. "Volumetric imaging of chick embryo heart development in vivo using a high speed Doppler spectral domain OCT microscope". Optics Infobase Conference Papers (January 1 , 2006.
Although embryonic MYH (eMYH) has been shown to be expressed in the myotome, skeletal muscle and chick heart late in development (from day 12) (Gulick et al., 1987; Lagrutta et al., 1989; Lyons et al., 1990; Merrifield et al., 1989; Sacks et al., 2003), expression during early cardiogenesis has not been determined.
Still, there is no direct evidence to demonstrate that cNkx2.8 can compensate for cNkx2.5 loss of function in early development of chick heart.
Expression studies localised eMYH in the developing chick heart.
When applied on ED4, metoprolol and carvedilol did not significantly affect Gs α levels in the developing chick heart.
Some early experiments with catecholamines and β-blockers revealed that the chick heart is more resistant to these drugs in early embryonic stages than in later stages of prenatal development [ 13].
I. Speed of movement of chick heart fibroblasts in relation to their mutual contacts.
Phosphorylation of the cardiac muscarinic receptor in intact chick heart and its regulation by a muscarinic agonist.
Mef2c is required for heart development [35].
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