Sentence examples for chemistry compounds from inspiring English sources

The diversity of natural products is greater than that of combinatorial chemistry compounds and is similar to that of drugs.

We have used a principal-component analysis (PCA) computational approach to analyze the 3D descriptor space of active and non-active (hit-like) cancer medicinal chemistry compounds.

Statistical standardization of target binding efficiencies relative to basal values obtained from a large background of medicinal chemistry compounds is proposed as a means to conciliate the concepts of binding efficiency and polypharmacology.

Finally, since natural products span regions of chemical space not represented by bioactive medicinal chemistry compounds [7], their scaffolds may serve as the inspiration for the design of structurally novel combinatorial libraries [8].

Organoboron chemicals have been employed in uses as diverse as boron carbide (see below), a complex very hard ceramic composed of boron-carbon cluster anions and cations, to carboranes, carbon-boron cluster chemistry compounds that can be halogenated to form reactive structures including carborane acid, a superacid.

We previously utilized an intein-based EPL technique to make BPA-containing Protein Z that is site-specifically modified at the C-terminus with functional moieties (e.g.., fluorescent dyes, click chemistry compounds, etc).

To understand the roles of efflux pumps in both the influx and efflux of compounds in P. aeruginosa and to aid the chemistry compound design by bridging in vitro enzymatic binding data (IC50 values) with whole cell results (MIC numbers), a collaborative effort was put forward to validate a series of bacterial penetration/accumulation assays for assessment of intracellular drug concentration.

A linear model relating compound abundances to total abundances leads to a new method of compound normalization, which in its turn reveals cyclic variations in abundance whose frequencies depend on chemistry (compound chain length and type) and environment (LD vs DD).

The development of small-molecule therapeutics by target-directed strategies has been accelerating due to the genome-driven discovery of new drug targets, the expansion of natural and synthetic combinatorial chemistry compound collections and the development of high- and ultra high-throughput screening (HTS) technologies [12], [13].

These mixtures included natural extracts, crude synthesis products, medicinal chemistry compound libraries, degradation products by light or harsh chemical conditions, as well as in vitro metabolic incubations.

These categories of smell are both very recognizable and very strongly linked to certain chemistry — sulfur compounds for garlic, ammonia compounds for fish — which made them particularly tractable.