Your English writing platform
Discover LudwigSuggestions(1)
Exact(4)
EPA's Endocrine Disruptor Screening Program Tier 1 battery consists of eleven assays intended to identify the potential of a chemical to interact with the estrogen, androgen, thyroid, or steroidogenesis systems.
These methods can estimate the capacity of a chemical to interact with a specific target and cause a biologic effect.
The Tier 1 battery assesses the potential of a chemical to interact with the endocrine system (specifically E, A, and T), and the Tier 2 assays are intended to identify possible effects within these systems.
Inverting the problem so that the vector now contains elements that represent the capacity of a single chemical to interact with each of a series of targets allows the most likely targets and, therefore, the most likely modes of toxicity for a specific chemical to be identified.
Similar(56)
EPA's Endocrine Disruptor Screening Program (EDSP) was implemented in 2009 2010 with the issuance of test orders requiring manufacturers and registrants of 58 pesticide active ingredients and nine pesticide inert/high production volume chemicals to evaluate the potential of these chemicals to interact with the estrogen, androgen and thyroid hormone systems.
Through OECD's joint EDTA working group a global platform for the harmonization and general acceptance of tests to assess the potential of chemicals to interact with the endocrine system has been generated.
To assess the ability of chemicals to interact with aPR, we performed commpetition binding assays with the synthetic progestin [3H]R5020.
The results demonstrate the feasibility of HTS to identify the potential for environmentally relevant chemicals to interact with key toxicity pathways related to human disease induction.
Conclusions: The results demonstrate the feasibility of qHTS to identify the potential for environmentally relevant chemicals to interact with key toxicity pathways related to human disease induction.
Both of these laws, the Food Quality Protection Act of 1996 (FQPA 1996) and the Safe Drinking Water Act Amendments of 1996 (SDWA Amendments 1996), contained provisions for assessing the potential for chemicals to interact with the endocrine system.
Conservation of molecular initiating events across species should enable nonmammalian vertebrate models to be used in determining the potential for chemicals to interact with the HPG axis in any vertebrate species (including humans), despite the fact that actual apical responses associated with endocrine disruption may differ across species.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com