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Tropsha was always interested in exploring the relation between chemical structure and function of compounds and in finding a cure for diseases.
Since the discovery of the chemical structure and function of DNA, there has been a material basis for biological information, satisfying (1) above (see also Collier and Hooker 1999; Brooks et al. 1989; Smith 1988 , 1998 2000).
"It's a tool that can now be used to address some very specific hypotheses... with regard to chemical structure and function".
Beside the clinical studies, in silico methods such as molecular modeling and computational mutagenesis techniques could establish a relationship between chemical structure and function of NCAN.
Microscopic examination (LM and FM) of LGT, on stems, leaf petioles, leaves and phyllaries of sunflower, showed the internal deposition of brownish and fluorescent substances of as yet unknown chemical structure and function (Fig. 2).
Chemical structure and function.
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To the best of our knowledge, little work has been reported from cheminformatics study for these especially pairwise datasets, which may provide insight into the mechanism of actions of the compounds and relationship between chemical structures and functions, as well as guidance for lead compound selection and optimization.
Using spectral libraries like BinBase [ 16] many of these metabolite peaks can be mapped to metabolites with known chemical structures and functions.
The chemical structures and functions of insect pheromones have been intensely studied because of the fascinating diversity of behavioral properties and relevance to questions of speciation, reproductive isolation, and applications to pest control (Witzgall et al., 2010).
Our findings provide new evidence showing the relationship between the chemical structure and biological function.
While the chemical structure and biological function of cyanophycin have been previously investigated, its material properties remain largely unexplored.
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