Sentence examples for chelators based on the from inspiring English sources

A new series of alkali chelators based on the structure of norbadione A has been reported.

Novel chelators based on the piperazino/side-bridged cyclam have been prepared and copper(ii) complexes formed.

Hence, we are interested in modified chelators based on the cyclam framework that also incorporate acetate arms but may have increased in vivo stability.

The incorporation of the NOTA chelator seems to have a minimal effect on the receptor binding affinity of the peptides [31].

The application of this technology to radiometal-based probes has lagged behind, however, most likely due to concerns over metal contamination by the catalyst itself, though "clickable" chelators based on both the Cu(I -catalyzed reactI -catalyzedreactionfree systems hand becotherore Cummon I -freelI -freere in recent yearsystems

We have recently demonstrated that tripodal hexadentate chelators, based on 3-hydroxy-4-pyridinone units, can limit the access of iron to bacteria and have a significant inhibitory effect in the intramacrophagic growth of Mycobacterium avium.

Alternative chelators for 68Ga3+ have been reported, including NOTA/NODAGA [19 22], TRAP and its derivatives [23 26], sarcophagines [27], HBED and its derivatives [6, 28], substituted 6-amino-perhydrodiazepines AAZTA [29], the siderophore FSC [30], and a series of chelators based on substituted pyridine carboxylates (DEDPA) [31 33].

It is well known that chelators based on oxime groups are able to complex uranyl cations efficiently.

We recently developed a chelating platform based on the macrocycle 1,4,7-triazacyclononane with up to three, five-membered azaheterocyclic arms for the development of 68Ga- and 64Cu-based radiopharmaceuticals. Here, a 68Ga-labelled conjugate comprising the bifunctional chelator NODIA-Me in combination with the αvß3-targeting peptide c RGDfK) has been synthesized and characterized.

Based on the DOTAGA chelator and the use of a d-amino acid spacer, compound 12 possesses remarkable potential for a PSMA based theranostics concept and is a suitable lead structure for the continuing development of PSMA ligands with further improved affinity.

Tsien and colleagues synthesized the first, rationally designed, fluorescent Ca2+ indicator for intracellular use based on the Ca2+-chelator EGTA [ 15].