Sentence examples for checkpoints function from inspiring English sources

These checkpoints function in concert to control the mitochondrion's and thus the cell's proper function.

As the checkpoints function to protect the cells from damage, it is hoped that their selective defect in tumor cells may result in sensitivity to novel therapeutic strategies.

Following DNA damage, cell cycle checkpoints function to prevent cell division and it seems possible that a similar function is being mediated through preventing (or simply slowing) cilia from being dismantled.

The functional recovery of the checkpoint function of CHFR was evaluated also in HCT116 cells after the exogenous introduction of wild type and mutant CHFR proteins.

This suggests that there is a functional link between the anti-proliferative effects and checkpoint function of CHFR.

Because sororin is required for functional cohesion, this result suggested that the G2/M checkpoint function of cohesin could be uncoupled from its function in sister-chromatid cohesion.

Such a detailed model may prove useful for predicting DNA damage G2 checkpoint function in cancer and, therefore, sensitivity to cancer therapy.

In a genetic screen to identify genes related to checkpoint function, we have characterized the role of rna14, an essential gene in the maintenance of chromosome dynamics.

Chk1 is required for spindle checkpoint function, both in normal and in taxol-treated cells [45].

Here we have tested critical aspects of the scaffolding model for Bub1 checkpoint function.

We have demonstrated that both of the conserved KEN boxes are important for Mad3p checkpoint function.